Sample size estimation in diagnostic test studies of biomedical informatics
نویسندگان
چکیده
منابع مشابه
Sample size estimation in epidemiologic studies
This review basically provided a conceptual framework for sample size calculation in epidemiologic studies with various designs and outcomes. The formula requirement of sample size was drawn based on statistical principles for both descriptive and comparative studies. The required sample size was estimated and presented graphically with different effect sizes and power of statistical test at 95...
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BACKGROUND The sample size required to power a study to a nominal level in a paired comparative diagnostic accuracy study, i.e. studies in which the diagnostic accuracy of two testing procedures is compared relative to a gold standard, depends on the conditional dependence between the two tests - the lower the dependence the greater the sample size required. A priori, we usually do not know the...
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OBJECTIVES To produce an easily understood and accessible tool for use by researchers in diagnostic studies. Diagnostic studies should have sample size calculations performed, but in practice, they are performed infrequently. This may be due to a reluctance on the part of researchers to use mathematical formulae. METHODS Using a spreadsheet, we derived nomograms for calculating the number of ...
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Planning studies involving diagnostic tests is complicated by the fact that virtually no test provides perfectly accurate results. The misclassification induced by imperfect sensitivities and specificities of diagnostic tests must be taken into account, whether the primary goal of the study is to estimate the prevalence of a disease in a population or to investigate the properties of a new diag...
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ژورنال
عنوان ژورنال: Journal of Biomedical Informatics
سال: 2014
ISSN: 1532-0464
DOI: 10.1016/j.jbi.2014.02.013